Intracellular Retention of Hepatitis B Virus Surface Proteins Reduces Interleukin-2 Augmentation after Genetic Immunizations

We have previously shown that hepatitis B virus (HBV) surface antigens (HBsAgs) are highly immunogenic after genetic immunization. Compared to the secreted middle HBV surface proteins (MHBs) or small HBV surface proteins (SHBs), the nonsecreted large HBV surface protein (LHBs), however, induced sign...

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Autori principali: Geissler, Michael, Bruss, Volker, Michalak, Sabine, Hockenjos, Birgit, Ortmann, Dörte, Offensperger, Wolf B., Wands, Jack R., Blum, Hubert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC104209/
https://ncbi.nlm.nih.gov/pubmed/10196326
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