Intracellular Retention of Hepatitis B Virus Surface Proteins Reduces Interleukin-2 Augmentation after Genetic Immunizations

We have previously shown that hepatitis B virus (HBV) surface antigens (HBsAgs) are highly immunogenic after genetic immunization. Compared to the secreted middle HBV surface proteins (MHBs) or small HBV surface proteins (SHBs), the nonsecreted large HBV surface protein (LHBs), however, induced sign...

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Main Authors: Geissler, Michael, Bruss, Volker, Michalak, Sabine, Hockenjos, Birgit, Ortmann, Dörte, Offensperger, Wolf B., Wands, Jack R., Blum, Hubert E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC104209/
https://ncbi.nlm.nih.gov/pubmed/10196326
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