Intracellular Retention of Hepatitis B Virus Surface Proteins Reduces Interleukin-2 Augmentation after Genetic Immunizations

We have previously shown that hepatitis B virus (HBV) surface antigens (HBsAgs) are highly immunogenic after genetic immunization. Compared to the secreted middle HBV surface proteins (MHBs) or small HBV surface proteins (SHBs), the nonsecreted large HBV surface protein (LHBs), however, induced sign...

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Bibliographische Detailangaben
Hauptverfasser: Geissler, Michael, Bruss, Volker, Michalak, Sabine, Hockenjos, Birgit, Ortmann, Dörte, Offensperger, Wolf B., Wands, Jack R., Blum, Hubert E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104209/
https://ncbi.nlm.nih.gov/pubmed/10196326
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