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Intracellular Retention of Hepatitis B Virus Surface Proteins Reduces Interleukin-2 Augmentation after Genetic Immunizations

We have previously shown that hepatitis B virus (HBV) surface antigens (HBsAgs) are highly immunogenic after genetic immunization. Compared to the secreted middle HBV surface proteins (MHBs) or small HBV surface proteins (SHBs), the nonsecreted large HBV surface protein (LHBs), however, induced sign...

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Detalhes bibliográficos
Main Authors: Geissler, Michael, Bruss, Volker, Michalak, Sabine, Hockenjos, Birgit, Ortmann, Dörte, Offensperger, Wolf B., Wands, Jack R., Blum, Hubert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104209/
https://ncbi.nlm.nih.gov/pubmed/10196326
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