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Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

Utilizing genetic modules of simple retroviruses, we have developed a novel generation of gene transfer vectors with improved therapeutic potential. In the 5′ untranslated “leader” sequences, all AUG codons which may aberrantly initiate translation and all viral coding sequences were removed. Thus,...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Hildinger, Markus, Abel, Kristin L., Ostertag, Wolfram, Baum, Christopher
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4083-4089.1999
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