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Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

Utilizing genetic modules of simple retroviruses, we have developed a novel generation of gene transfer vectors with improved therapeutic potential. In the 5′ untranslated “leader” sequences, all AUG codons which may aberrantly initiate translation and all viral coding sequences were removed. Thus,...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Hildinger, Markus, Abel, Kristin L., Ostertag, Wolfram, Baum, Christopher
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104187/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196304/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4083-4089.1999
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