Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

Utilizing genetic modules of simple retroviruses, we have developed a novel generation of gene transfer vectors with improved therapeutic potential. In the 5′ untranslated “leader” sequences, all AUG codons which may aberrantly initiate translation and all viral coding sequences were removed. Thus,...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Hildinger, Markus, Abel, Kristin L., Ostertag, Wolfram, Baum, Christopher
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1999
Fag:	Gene Therapy
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104187/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.4083-4089.1999
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