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Irreversible Inhibition of Human Immunodeficiency Virus Type 1 Integrase by Dicaffeoylquinic Acids

Human immunodeficiency virus type 1 (HIV-1) and other retroviruses require integration of a double-stranded DNA copy of the RNA genome into the host cell chromosome for productive infection. The viral enzyme, integrase, catalyzes the integration of retroviral DNA and represents an attractive target...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Kai, Cordeiro, Mara L., Atienza, Jocelyn, Robinson, W. Edward, Chow, Samson A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104095/
https://ncbi.nlm.nih.gov/pubmed/10074185
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