Irreversible Inhibition of Human Immunodeficiency Virus Type 1 Integrase by Dicaffeoylquinic Acids

Human immunodeficiency virus type 1 (HIV-1) and other retroviruses require integration of a double-stranded DNA copy of the RNA genome into the host cell chromosome for productive infection. The viral enzyme, integrase, catalyzes the integration of retroviral DNA and represents an attractive target...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zhu, Kai, Cordeiro, Mara L., Atienza, Jocelyn, Robinson, W. Edward, Chow, Samson A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3309-3316.1999
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