CCR5-Mediated Human Immunodeficiency Virus Entry Depends on an Amino-Terminal gp120-Binding Site and on the Conformational Integrity of All Four Extracellular Domains

The human immunodeficiency virus type 1 coreceptor activity of CCR5 depends on certain polar and charged residues in its amino-terminal domain. Since studies of chimeric receptors have indicated that the extracellular loops of CCR5 are also involved in viral fusion and entry, we have explored the ro...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Genoud, Stéphane, Kajumo, Francis, Guo, Yong, Thompson, Daniah, Dragic, Tatjana
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1645-1648.1999
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