A Novel Role for Escherichia coli Endonuclease VIII in Prevention of Spontaneous G→T Transversions

In the bacterium Escherichia coli, oxidized pyrimidines are removed by two DNA glycosylases, endonuclease III and endonuclease VIII (endo VIII), encoded by the nth and nei genes, respectively. Double mutants lacking both of these activities exhibit a high spontaneous mutation frequency, and here we...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Blaisdell, Jeffrey O., Hatahet, Zafer, Wallace, Susan S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10515930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.20.6396-6402.1999
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