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A Novel Role for Escherichia coli Endonuclease VIII in Prevention of Spontaneous G→T Transversions

In the bacterium Escherichia coli, oxidized pyrimidines are removed by two DNA glycosylases, endonuclease III and endonuclease VIII (endo VIII), encoded by the nth and nei genes, respectively. Double mutants lacking both of these activities exhibit a high spontaneous mutation frequency, and here we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Blaisdell, Jeffrey O., Hatahet, Zafer, Wallace, Susan S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC103775/
https://ncbi.nlm.nih.gov/pubmed/10515930
Tagiau: Ychwanegu Tag
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