A Novel Role for Escherichia coli Endonuclease VIII in Prevention of Spontaneous G→T Transversions

In the bacterium Escherichia coli, oxidized pyrimidines are removed by two DNA glycosylases, endonuclease III and endonuclease VIII (endo VIII), encoded by the nth and nei genes, respectively. Double mutants lacking both of these activities exhibit a high spontaneous mutation frequency, and here we...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Bacteriol
Autori principali:	Blaisdell, Jeffrey O., Hatahet, Zafer, Wallace, Susan S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10515930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.20.6396-6402.1999
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!