Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate

Endonuclease VIII (Nei) of Escherichia coli is a DNA repair enzyme that excises oxidized pyrimidines from DNA. Nei shares with formamidopyrimidine-DNA glycosylase (Fpg) sequence homology and a similar mechanism of action: the latter involves removal of the damaged base followed by two sequential β-e...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Zharkov, Dmitry O., Golan, Gali, Gilboa, Rotem, Fernandes, Andrea S., Gerchman, Sue Ellen, Kycia, Jadwiga H., Rieger, Robert A., Grollman, Arthur P., Shoham, Gil
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11847126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.4.789
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