Structural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate

Endonuclease VIII (Nei) of Escherichia coli is a DNA repair enzyme that excises oxidized pyrimidines from DNA. Nei shares with formamidopyrimidine-DNA glycosylase (Fpg) sequence homology and a similar mechanism of action: the latter involves removal of the damaged base followed by two sequential β-e...

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Bibliographic Details
Main Authors: Zharkov, Dmitry O., Golan, Gali, Gilboa, Rotem, Fernandes, Andrea S., Gerchman, Sue Ellen, Kycia, Jadwiga H., Rieger, Robert A., Grollman, Arthur P., Shoham, Gil
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125349/
https://ncbi.nlm.nih.gov/pubmed/11847126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.789
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