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Retro-recombination screening of a mouse embryonic stem cell genomic library

Targeted gene disruption is an important tool in molecular medicine, allowing for the generation of animal models of human disease. Conventional methods of targeting vector (TV) construction are difficult and represent a rate limiting step in any targeting experiment. We previously demonstrated that...

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Detalhes bibliográficos
Main Authors: Woltjen, Knut, Bain, Gerard, Rancourt, Derrick E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103314/
https://ncbi.nlm.nih.gov/pubmed/10756208
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