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Retro-recombination screening of a mouse embryonic stem cell genomic library
Targeted gene disruption is an important tool in molecular medicine, allowing for the generation of animal models of human disease. Conventional methods of targeting vector (TV) construction are difficult and represent a rate limiting step in any targeting experiment. We previously demonstrated that...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC103314/ https://ncbi.nlm.nih.gov/pubmed/10756208 |
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