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Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens
Forward genetic screens using mammalian embryonic stem (ES) cells have identified genes required for numerous cellular processes. However, loss-of-function screens are more difficult to conduct in diploid cells because, in most cases, both alleles of a gene must be mutated to exhibit a phenotype. Re...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5727442/ https://ncbi.nlm.nih.gov/pubmed/29036617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx857 |
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