Site-specific modification and RNA crosslinking of the RNA-binding domain of PKR
RNA-dependent protein kinase (PKR) is an interferon-induced, RNA-activated enzyme that phosphorylates and inhibits the function of the translation initiation factor eIF-2. PKR is activated in vitro by binding RNA molecules with extensive duplex structure. To further define the nature of the RNA regu...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756189/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.9.1899 |
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