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Site-specific modification and RNA crosslinking of the RNA-binding domain of PKR

RNA-dependent protein kinase (PKR) is an interferon-induced, RNA-activated enzyme that phosphorylates and inhibits the function of the translation initiation factor eIF-2. PKR is activated in vitro by binding RNA molecules with extensive duplex structure. To further define the nature of the RNA regu...

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Pubblicato in:Nucleic Acids Res
Autori principali: Spanggord, Richard J., Beal, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756189/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.9.1899
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