DNA binding mode of the Fab fragment of a monoclonal antibody specific for cyclobutane pyrimidine dimer

Monoclonal antibodies specific for the cyclobutane pyrimidine dimer (CPD) are widely used for detection and quantification of DNA photolesions. However, the mechanisms of antigen binding by anti-CPD antibodies are little understood. Here we report NMR analyses of antigen recognition by TDM-2, which...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Torizawa, Takuya, Yamamoto, Nobuhiro, Suzuki, Tomonori, Nobuoka, Kaoru, Komatsu, Yasuo, Morioka, Hiroshi, Nikaido, Osamu, Ohtsuka, Eiko, Kato, Koichi, Shimada, Ichio
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2000
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648787/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.4.944
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