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UVA-induced cyclobutane pyrimidine dimers form predominantly at thymine–thymine dipyrimidines and correlate with the mutation spectrum in rodent cells

Ligation-mediated PCR was employed to quantify cyclobutane pyrimidine dimer (CPD) formation at nucleotide resolution along exon 2 of the adenine phosphoribosyltransferase (aprt) locus in Chinese hamster ovary (CHO) cells following irradiation with either UVA (340–400 nm), UVB (295–320 nm), UVC (254...

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Detalhes bibliográficos
Main Authors: Rochette, Patrick J., Therrien, Jean-Philippe, Drouin, Régen, Perdiz, Daniel, Bastien, Nathalie, Drobetsky, Elliot A., Sage, Evelyne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156735/
https://ncbi.nlm.nih.gov/pubmed/12771205
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