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DNA binding mode of the Fab fragment of a monoclonal antibody specific for cyclobutane pyrimidine dimer

Monoclonal antibodies specific for the cyclobutane pyrimidine dimer (CPD) are widely used for detection and quantification of DNA photolesions. However, the mechanisms of antigen binding by anti-CPD antibodies are little understood. Here we report NMR analyses of antigen recognition by TDM-2, which...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Torizawa, Takuya, Yamamoto, Nobuhiro, Suzuki, Tomonori, Nobuoka, Kaoru, Komatsu, Yasuo, Morioka, Hiroshi, Nikaido, Osamu, Ohtsuka, Eiko, Kato, Koichi, Shimada, Ichio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.4.944
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