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Naturally occurring mutations in the human HNF4α gene impair the function of the transcription factor to a varying degree

The hepatocyte nuclear factor (HNF)4α, a member of the nuclear receptor superfamily, regulates genes that play a critical role in embryogenesis and metabolism. Recent studies have shown that mutations in the human HNF4α gene cause a rare form of type 2 diabetes, maturity onset diabetes of the young...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lausen, Jörn, Thomas, Heike, Lemm, Ira, Bulman, Michael, Borgschulze, Michael, Lingott, Anja, Hattersley, Andrew T., Ryffel, Gerhart U.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC102517/
https://ncbi.nlm.nih.gov/pubmed/10606640
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