The mutated human gene encoding hepatocyte nuclear factor 1β inhibits kidney formation in developing Xenopus embryos

The transcription factor hepatocyte nuclear factor 1β (HNF1β) is a tissue-specific regulator that also plays an essential role in early development of vertebrates. In humans, four heterozygous mutations in the HNF1β gene have been identified that lead to early onset of diabetes and severe primary re...

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Detaylı Bibliyografya
Asıl Yazarlar: Wild, Wiltrud, Pogge von Strandmann, Elke, Nastos, Aristotelis, Senkel, Sabine, Lingott-Frieg, Anja, Bulman, Michael, Bingham, Coralie, Ellard, Sian, Hattersley, Andrew T., Ryffel, Gerhart U.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC18295/
https://ncbi.nlm.nih.gov/pubmed/10758154
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