The mutated human gene encoding hepatocyte nuclear factor 1β inhibits kidney formation in developing Xenopus embryos

The transcription factor hepatocyte nuclear factor 1β (HNF1β) is a tissue-specific regulator that also plays an essential role in early development of vertebrates. In humans, four heterozygous mutations in the HNF1β gene have been identified that lead to early onset of diabetes and severe primary re...

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Detalhes bibliográficos
Main Authors: Wild, Wiltrud, Pogge von Strandmann, Elke, Nastos, Aristotelis, Senkel, Sabine, Lingott-Frieg, Anja, Bulman, Michael, Bingham, Coralie, Ellard, Sian, Hattersley, Andrew T., Ryffel, Gerhart U.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18295/
https://ncbi.nlm.nih.gov/pubmed/10758154
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