DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease
To investigate the effect of nucleosomes on nucleotide excision repair in humans, we prepared a mononucleosome containing a (6-4) photoproduct in the nucleosome core and examined its repair with the reconstituted human excision nuclease system and with cell extracts. Nucleosomal DNA is repaired at a...
שמור ב:
| הוצא לאור ב: | Mol Cell Biol |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Taylor & Francis
2000
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9173-9181.2000 |
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