DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease

To investigate the effect of nucleosomes on nucleotide excision repair in humans, we prepared a mononucleosome containing a (6-4) photoproduct in the nucleosome core and examined its repair with the reconstituted human excision nuclease system and with cell extracts. Nucleosomal DNA is repaired at a...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Hara, Ryujiro, Mo, Jinyao, Sancar, Aziz
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 2000
Pynciau:	DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9173-9181.2000
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