DNA Damage in the Nucleosome Core Is Refractory to Repair by Human Excision Nuclease

To investigate the effect of nucleosomes on nucleotide excision repair in humans, we prepared a mononucleosome containing a (6-4) photoproduct in the nucleosome core and examined its repair with the reconstituted human excision nuclease system and with cell extracts. Nucleosomal DNA is repaired at a...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Hara, Ryujiro, Mo, Jinyao, Sancar, Aziz
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2000
Schlagworte:	DNA Dynamics and Chromosome Structure
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9173-9181.2000
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!