An in vivo selection system for homing endonuclease activity

Homing endonucleases are enzymes that catalyze the highly sequence-specific cleavage of DNA. We have developed an in vivo selection in Escherichia coli that links cell survival with homing endonuclease-mediated DNA cleavage activity and sequence specificity. Using this selection, wild-type and mutan...

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-д хэвлэсэн:	Nucleic Acids Res
Үндсэн зохиолчид:	Gruen, Mathias, Chang, Kathy, Serbanescu, Irina, Liu, David R.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Oxford University Press 2002
Нөхцлүүд:	NAR Methods Online
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.e29
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