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An in vivo selection system for homing endonuclease activity

Homing endonucleases are enzymes that catalyze the highly sequence-specific cleavage of DNA. We have developed an in vivo selection in Escherichia coli that links cell survival with homing endonuclease-mediated DNA cleavage activity and sequence specificity. Using this selection, wild-type and mutan...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Nucleic Acids Res
Ngā kaituhi matua: Gruen, Mathias, Chang, Kathy, Serbanescu, Irina, Liu, David R.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Oxford University Press 2002
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.e29
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