An in vivo selection system for homing endonuclease activity
Homing endonucleases are enzymes that catalyze the highly sequence-specific cleavage of DNA. We have developed an in vivo selection in Escherichia coli that links cell survival with homing endonuclease-mediated DNA cleavage activity and sequence specificity. Using this selection, wild-type and mutan...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.e29 |
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