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Analysis of Genes Expressed at the Infective Larval Stage Validates Utility of Litomosoides sigmodontis as a Murine Model for Filarial Vaccine Development

We used an expressed sequence tag approach to analyze genes expressed by the infective larvae of the rodent filarial parasite Litomosoides sigmodontis. One hundred fifty two new genes were identified, including several proposed as vaccine candidates in studies with human filarial parasites. Our find...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allen, Judith E., Daub, Jennifer, Guiliano, David, McDonnell, Amanda, Lizotte-Waniewski, Michelle, Taylor, David W., Blaxter, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC101817/
https://ncbi.nlm.nih.gov/pubmed/10948183
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