Analysis of Genes Expressed at the Infective Larval Stage Validates Utility of Litomosoides sigmodontis as a Murine Model for Filarial Vaccine Development

We used an expressed sequence tag approach to analyze genes expressed by the infective larvae of the rodent filarial parasite Litomosoides sigmodontis. One hundred fifty two new genes were identified, including several proposed as vaccine candidates in studies with human filarial parasites. Our find...

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Detalhes bibliográficos
Main Authors: Allen, Judith E., Daub, Jennifer, Guiliano, David, McDonnell, Amanda, Lizotte-Waniewski, Michelle, Taylor, David W., Blaxter, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC101817/
https://ncbi.nlm.nih.gov/pubmed/10948183
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