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Analysis of Genes Expressed at the Infective Larval Stage Validates Utility of Litomosoides sigmodontis as a Murine Model for Filarial Vaccine Development

We used an expressed sequence tag approach to analyze genes expressed by the infective larvae of the rodent filarial parasite Litomosoides sigmodontis. One hundred fifty two new genes were identified, including several proposed as vaccine candidates in studies with human filarial parasites. Our find...

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Main Authors: Allen, Judith E., Daub, Jennifer, Guiliano, David, McDonnell, Amanda, Lizotte-Waniewski, Michelle, Taylor, David W., Blaxter, Mark
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC101817/
https://ncbi.nlm.nih.gov/pubmed/10948183
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