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Analysis of Genes Expressed at the Infective Larval Stage Validates Utility of Litomosoides sigmodontis as a Murine Model for Filarial Vaccine Development

We used an expressed sequence tag approach to analyze genes expressed by the infective larvae of the rodent filarial parasite Litomosoides sigmodontis. One hundred fifty two new genes were identified, including several proposed as vaccine candidates in studies with human filarial parasites. Our find...

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Publicat a:Infect Immun
Autors principals: Allen, Judith E., Daub, Jennifer, Guiliano, David, McDonnell, Amanda, Lizotte-Waniewski, Michelle, Taylor, David W., Blaxter, Mark
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101817/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10948183/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.9.5454-5458.2000
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