Direct Evidence for Involvement of NF-κB in Transcriptional Activation of Tumor Necrosis Factor by a Spirochetal Lipoprotein

Variable major lipoprotein (Vmp) is a major tumor necrosis factor (TNF)-inducing component of Borrelia recurrentis, the agent of louse-borne relapsing fever. B. recurrentis Vmp rapidly stimulates nuclear translocation of NF-κB and proinflammatory cytokine gene expression in the human monocyte-like c...

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Detalles Bibliográficos
Main Authors: Udalova, Irina A., Vidal, Vincent, Scragg, Ian G., Kwiatkowski, Dominic
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC101815/
https://ncbi.nlm.nih.gov/pubmed/10948181
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