β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
In addition to their roles in desensitization and signaling of seven-membrane-spanning receptors, β-arrestins have been more recently implicated in regulating non-seven-membrane-spanning receptor pathways. By using a yeast two-hybrid screen, we identified the inhibitor of NF-κB, IκBα, as a binding p...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15173580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402851101 |
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