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Pseudomonas aeruginosa ExoT Is a Rho GTPase-Activating Protein
Transient intracellular expression of ExoT in CHO cells stimulated cell rounding and actin reorganization. Biochemical studies showed that ExoT was a GTPase-activating protein for RhoA, Rac1, and Cdc42. Together, these data show that ExoT interferes with Rho signal transduction pathways, which regul...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
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American Society for Microbiology
2000
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC101576/ https://ncbi.nlm.nih.gov/pubmed/10992524 |
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