Pseudomonas aeruginosa ExoT Is a Rho GTPase-Activating Protein

Transient intracellular expression of ExoT in CHO cells stimulated cell rounding and actin reorganization. Biochemical studies showed that ExoT was a GTPase-activating protein for RhoA, Rac1, and Cdc42. Together, these data show that ExoT interferes with Rho signal transduction pathways, which regul...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Krall, Rebecca, Schmidt, Gudula, Aktories, Klaus, Barbieri, Joseph T.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2000
Pynciau:	Molecular and Cellular Pathogenesis
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.6066-6068.2000
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