Pseudomonas aeruginosa ExoT Is a Rho GTPase-Activating Protein
Transient intracellular expression of ExoT in CHO cells stimulated cell rounding and actin reorganization. Biochemical studies showed that ExoT was a GTPase-activating protein for RhoA, Rac1, and Cdc42. Together, these data show that ExoT interferes with Rho signal transduction pathways, which regul...
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| Publicado no: | Infect Immun |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10992524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.10.6066-6068.2000 |
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