The contribution of 2′-hydroxyls to the cleavage activity of the Neurospora VS ribozyme
We have used nucleotide analog interference mapping and site-specific substitution to determine the effect of 2′-deoxynucleotide substitution of each nucleotide in the VS ribozyme on the self-cleavage reaction. A large number of 2′-hydroxyls (2′-OHs) that contribute to cleavage activity of the VS ri...
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| Vydáno v: | Nucleic Acids Res |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11861903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.5.1132 |
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