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hMutSα forms an ATP-dependent complex with hMutLα and hMutLβ on DNA

The DNA binding properties of hMutSα and hMutLα and complex formation of hMutSα with hMutLα and hMutLβ were investigated using binding experiments on magnetic bead-coupled DNA substrates with nuclear extracts as well as purified proteins. hMutSα binding to homoduplex DNA was disrupted by lower NaCl...

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Main Authors: Plotz, Guido, Raedle, Jochen, Brieger, Angela, Trojan, Jörg, Zeuzem, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC100294/
https://ncbi.nlm.nih.gov/pubmed/11809883
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