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Involvement of Brca1 in S-Phase and G(2)-Phase Checkpoints after Ionizing Irradiation

Cell cycle arrests in the G(1), S, and G(2) phases occur in mammalian cells after ionizing irradiation and appear to protect cells from permanent genetic damage and transformation. Though Brca1 clearly participates in cellular responses to ionizing radiation (IR), conflicting conclusions have been d...

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Bibliografiske detaljer
Main Authors: Xu, Bo, Kim, Seong-tae, Kastan, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC100266/
https://ncbi.nlm.nih.gov/pubmed/11313470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.10.3445-3450.2001
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