Protein Binding Protects Sites on Stable Episomes and in the Chromosome from De Novo Methylation

We have utilized the Escherichia coli lac repressor-operator system to test whether protein binding can interfere with de novo DNA methylation in mammalian cells. We find that a DNA binding protein can protect sites on the episome as well as in the genome from the de novo methylation activity of Dnm...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Han, Li, Lin, Iping G., Hsieh, Chih-Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11313467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.10.3416-3424.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!