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Evidence that Protein Binding Specifies Sites of DNA Demethylation

It has been hypothesized that protein factors may protect CpG islands from methyltransferase during development and that demethylation may involve protein-DNA interactions at demethylated sites. However, direct evidence has been lacking. In this study, demethylation at the EBNA-1 binding sites of th...

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Autor principal: Hsieh, Chih-Lin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC83864/
https://ncbi.nlm.nih.gov/pubmed/9858530
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