Dual Role of Lipopolysaccharide (LPS)-Binding Protein in Neutralization of LPS and Enhancement of LPS-Induced Activation of Mononuclear Cells

The lipopolysaccharide (LPS)-binding protein (LBP) has a concentration-dependent dual role in the pathogenesis of gram-negative sepsis: low concentrations of LBP enhance the LPS-induced activation of mononuclear cells (MNC), whereas the acute-phase rise in LBP concentrations inhibits LPS-induced cel...

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Detalhes bibliográficos
Main Authors: Gutsmann, Thomas, Müller, Mareike, Carroll, Stephen F., MacKenzie, Roger C., Wiese, Andre, Seydel, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100074/
https://ncbi.nlm.nih.gov/pubmed/11598069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.11.6942-6950.2001
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