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Dual Role of Lipopolysaccharide (LPS)-Binding Protein in Neutralization of LPS and Enhancement of LPS-Induced Activation of Mononuclear Cells

The lipopolysaccharide (LPS)-binding protein (LBP) has a concentration-dependent dual role in the pathogenesis of gram-negative sepsis: low concentrations of LBP enhance the LPS-induced activation of mononuclear cells (MNC), whereas the acute-phase rise in LBP concentrations inhibits LPS-induced cel...

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Udgivet i:Infect Immun
Principais autores: Gutsmann, Thomas, Müller, Mareike, Carroll, Stephen F., MacKenzie, Roger C., Wiese, Andre, Seydel, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC100074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598069/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.11.6942-6950.2001
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