Serum Amyloid P Component Bound to Gram-Negative Bacteria Prevents Lipopolysaccharide-Mediated Classical Pathway Complement Activation

Although serum amyloid P component (SAP) is known to bind many ligands, its biological function is not yet clear. Recently, it was demonstrated that SAP binds to lipopolysaccharide (LPS). In the present study, SAP was shown to bind to gram-negative bacteria expressing short types of LPS or lipo-olig...

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Hlavní autoři: de Haas, Carla J. C., van Leeuwen, Ester M. M., van Bommel, Toon, Verhoef, Jan, van Kessel, Kok P. M., van Strijp, Jos A. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97344/
https://ncbi.nlm.nih.gov/pubmed/10722560
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