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Serum Amyloid P Component Bound to Gram-Negative Bacteria Prevents Lipopolysaccharide-Mediated Classical Pathway Complement Activation

Although serum amyloid P component (SAP) is known to bind many ligands, its biological function is not yet clear. Recently, it was demonstrated that SAP binds to lipopolysaccharide (LPS). In the present study, SAP was shown to bind to gram-negative bacteria expressing short types of LPS or lipo-olig...

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Bibliografske podrobnosti
Main Authors: de Haas, Carla J. C., van Leeuwen, Ester M. M., van Bommel, Toon, Verhoef, Jan, van Kessel, Kok P. M., van Strijp, Jos A. G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC97344/
https://ncbi.nlm.nih.gov/pubmed/10722560
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