Serum Amyloid P Component Bound to Gram-Negative Bacteria Prevents Lipopolysaccharide-Mediated Classical Pathway Complement Activation

Although serum amyloid P component (SAP) is known to bind many ligands, its biological function is not yet clear. Recently, it was demonstrated that SAP binds to lipopolysaccharide (LPS). In the present study, SAP was shown to bind to gram-negative bacteria expressing short types of LPS or lipo-olig...

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Main Authors: de Haas, Carla J. C., van Leeuwen, Ester M. M., van Bommel, Toon, Verhoef, Jan, van Kessel, Kok P. M., van Strijp, Jos A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97344/
https://ncbi.nlm.nih.gov/pubmed/10722560
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