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Fbw7/hCDC4 dimerization regulates its substrate interactions
<p>Abstract</p> <p>Background</p> <p>The Fbw7 ubiquitin ligase promotes the rapid degradation of several important oncogenes, such as cyclin E, c-Myc, c-Jun, and Notch. The two fission yeast homologs of Fbw7, pop1 and pop2, have previously been shown to dimerize. In thi...
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Hlavní autoři: | , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
BMC
2007-02-01
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Edice: | Cell Division |
On-line přístup: | http://www.celldiv.com/content/2/1/7 |
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