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<it>BRAF </it>and <it>RAS </it>oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study

<p>Abstract</p> <p>Background</p> <p>Colorectal cancer is a common disease that involves genetic alterations, such as inactivation of tumour suppressor genes and activation of oncogenes. Among them are RAS and BRAF mutations, which rarely coexist in the same tumour. Ind...

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Bibliographic Details
Main Authors: Shirasawa Senji, Sasazuki Takehiko, Andera Ladislav, Koc Michal, Oikonomou Eftychia, Makrodouli Eleni, Pintzas Alexander
Format: Artigo
Language:Inglês
Published: BMC 2011-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/118
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